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I am having the same problem. Quickbooks is not able to see my installed printer. All the other XP applications I am running have no problem...
I'm now running build 9344 and so far so good!
By the way if the problem was with Snow Leopard, PD Version 4 wouldn't run right either.
I upgraded Version 5 the week it was released. It ran fine for a week or so then started getting slower and slower until it took about 5 minutes...
Unfortunately I'm dealing with the same problem. I've made the changes to Spotlight and it seems to help (so far). Still a bit slow on startup. So...