If you run Matlab R2020b while Parallels Access is running in the background, and you try to close a figure manually, Matlab will freeze and crash. This problem would not happen if you quit Parallels Access, or disable the accessibility API of Parallels Access in System Preferences -> Security and Privacy -> Accessibility. This is presumably not a bug of Parallels Access, but of Matlab. The same problem is also reported in Matlab Answers: https://www.mathworks.com/matlabcentral/answers/646743-matlab-2020b-crashes-everytime-i-close-a-figure-manually https://www.mathworks.com/matlabcentral/answers/480796-not-responding-on-startup-macos-mojave Hope that this thread could help who encounter this problem.