Installing PD4 on a MacPro with 8GB Ram and 10.5.5 into the BootCamp partition, where I have Vista x64 installed (clean - no Parallels installation before. No Parallels tools yet, obviously). Don't know if it matters, but I had MacFUSE and NTFS-3G installed on OS X. 1st issue - The mouse wouldn't work at all. If I unplug and re-plug it, I can select the VM and then have the mouse in the VM. This was needed to click okay to installing unsigned drivers. 2nd issue - At the end, the shutdown took forever. As the VM rebooted, Parallels said that it cannot see HDD1. It then sits at a prompt trying to do DHCP. As an aside - I then booted into BootCamp and the parallels tools installer tried to run, but said it cannot communicate with the VM and rebooted for me. 3rd issue - When I booted into BootCamp, Vista kept telling me that the disc is corrupted and that there are issues with \$Mft. I had to boot off of the install disk and run chkdsk to fix these issues. I uninstalled NTFS-3G and tried to create a new VM, again into BootCamp. This time, the network wouldn't work and Parallels tools says it can't install because it says it needs the network to install. I still had the mouse issue. I could, when the mouse is active in OS X click on the USB icon on the VM window and check the mouse (connected to the keyboard btw) to make the mouse work in the VM. Obviously then pressing CTRL-ALT didn't return the mouse to OS X. I would have to unplug and re-plug it again. I did wait considerable time, as prompted, before I tried to log in so that the keyboard and mouse can be set up. Maybe not long enough? On the plus side, I then tried doing this on a machine with XP BootCamp tonight, and that worked like a charm. I didn't see any unsigned driver dialogs. I just let it sit, after clicking my login and it went through its paces, rebooted and all was well, with XP BootCamp. Bottom line - after several attempts, I could not get Vista x64 in BootCamp to work, at all.