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Have you tried clearing the PRAM (hold command-option-p-r on boot until you hear the chime at least twice)? This will clear out all settings....
I'm assuming you are using USB-to-serial adapters. When you add the virtual serial ports in the VM hardware configuration, are you pointing to...
First troubleshooting step is to always try reinstalling Parallels Tools from the Virtual Machine menu. Steve
Virtual Machine menu -> Configure -> Options -> Full Screen Are you using Mac OS X full screen mode or not? What do you have Scale to fit...