I'm having issues on Windows 8 Pro with the Windows 2X Client.
After I install the 2X client, it performs wonderfully, even going so far as to place icons for applications in the start menu after connecting the first time.
Unfortunately when I restart the machine after the install the machine seems to get caught in some sort of loop upon booting again, where a blue screen will start to appear but will flicker the display like it is refreshing. It is as far as I can tell impossible to continue on to Windows and try to resolve the issue, and my attempts to access safe mode also fail (thought that may have more to do with my BIOS, which is catching me rapidly tapping the F8 key and errors out, claiming it is a stuck key on the machine).
The fastest way I have right now to resolve the issue is to load up the Windows 8 install media and perform a "Refresh" that automatically wipes the 2X client from the machine, as well as any other desktop-installed software.
I initially thought this was an issue with the NVIDIA video drivers due to the 'flickering' nature of the screen, but I tried three different versions of their drivers and even disabling them entirely and I cannot reproduce this issue without the 2X client being installed.
Running: Thinkpad T410, 64-bit Windows 8 Pro. NVIDIA NVS 3100M graphics.
Installing: 2X Client for Windows 64-bit v10.5.1323