The solution is to deactivate the "activate trim" function of the virtual hard disk. I don't know, why this function suddenly causes these problems. Without trim functionality everything works normal. After reactivate the "activate trim", parallels starts immediately after starting the virtual W10 reading over the last 30 Minutes more than 60 Gigabytes and more and the Mac and the W10 ist nearly not usable.
Last edited: Nov 21, 2017