Hi Manoj,
I deleted and re-installed as you had suggested with no result. I have noticed that the issue pertains only to Windows programs while in coherence and it's always when the program first starts up. Additional information is that I am using the Bose Companion 5 system which employs connectivity via USB port. This is directly connected to my Mac not a hub. I did contact Bose support and they had said they really have not done any extensive testing in VM's. Wondering if anyone else has experienced this issue?