AVX/AVX2 instructions + DirectX 12

In other words, the game developer was paid to use something exclusive to Windows on the intel architecture and they are unlikely to migrate the game to a better platform.

 

Exactly. They have been building for x86/64 for so long and are so tied to Windows/Intel technology ( and OpenGL which just won't die) the engineering effort is too high.

 

I have had success playing games using CrossOver that would not play correctly in Parallels Desktop.

 

If your software explicitly checks for "AVX support" or "DX12 full feature level" (versus DX11/feature level fallback), you'll likely hit a wall for now using Parallels on Apple Silicon.